cyclophosphamide will increase the amount or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified. modafinil will improve the amount or impact of pantoprazole by influencing hepatic enzyme CYP2C19 metabolism. Insignificant/Importance

Pediatric Use: Performance and safety in pediatric individuals are certainly not set up. Modafinil is not really FDA-permitted for use from the pediatric inhabitants for virtually any indication. A examine with a situation number of three individuals in an institution’s Thoracic Surgica

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They discovered which the 5-HT3 receptor antagonist MDL72222 by itself was in a position to attenuate this effect Just about around the general serotonin antagonist methysergide, indicating that modafinil worked to decrease GABA partly by way of a serotonergic pathway mediated generally through